Beta-lactam antibiotics (based on penicillins, cephalosporins, monobactams, carbapenems and beta-lactamase inhibitors) are antibiotics worldwide as the first line of treatment for various infections.
But today, penicillin is an antibiotic that kills bacteria.
As he explained Dr. Nancy OrtegaPresident of the Drug Allergy Committee of Spanish Society of Allergology and Clinical Immunology (SEAIC):
- “In general, the drugs that most often cause allergic reactions in adults are penicillin and non-steroidal anti-inflammatory drugs. For children, penicillin is the first line.
However, it is not always a sign of being allergies to penicillin or beta-lactam antibiotics is similar to actual hypersensitivity to these antibiotics in humans.
In some cases, these types of antibiotics can cause complications that are not related to the immune system, such as allergies.
Archive – He warns that the misuse of antibiotics is making them ineffective five years ago. / ASEBIO – Archive
Very much, as we have explained Dr. Esther Morenomember of the SEAIC Drug Allergy Committee:
- “Between 70% and 95% of patients known to be allergic to penicillin will not be allergic to the drug.”
And this represents a serious problem for the patient and health, since to say that a person is allergic to penicillin or beta-lactam antibiotics means that they have to be given other types of drugs that are less effective and/or more toxic. expensive.
Then, A penicillin allergy symptom is:
- Long-term hospitalization
- The maximum number of readings
- Advanced medical expenses
- And/or death, according to several studies is done by patients in the hospital.
“Improving antimicrobial stewardship for patients with antimicrobial resistance has been one of the most important aspects of the antimicrobial stewardship program.BOW) in several countries,” said the expert.
Antibiotics can cause severe itching that is not related to allergies.
Complete allergy education to prevent allergic reactions to antibiotics
The first step in the management of patients treated with beta-lactam antibiotics should be to identify those who are mislabeled due to drug complications that are not related to immune system disorders.
As Dr. Moreno explains:
- “The standard for identifying a patient with symptoms of allergy to penicillin or another beta-lactam is to perform a full allergy test, including skin testing and testing for exposure to the antibiotics involved or other methods.”
This type of training is the only way to determine the cause of the disease and allows, in most cases, to prevent the allergy and eliminate the symptom.
“For patients with confirmed allergies, cross-reactivity research will allow the use of certain drugs in many patients. All of this will help improve the selection of antibiotics and improve the clinical outcomes of these patients when they need antibiotics,” concludes the expert.
The correct diagnosis of drug allergy is very important, because, using any other drug can have various side effects that damage the health of the patient.
And the main results will be:
- “The increase in drug failure
- The presence of unwanted effects
- Increasing prevalence of antibiotic-resistant infections
- The growth of money, because certain drugs have a high price
- He will spend a long time in the hospital.”
The side effects of drugs used in cancer and inflammatory diseases are increasing.
Increasing the severity of the action of other drugs
Most severe drug reactions are not due to the immunological mechanism, and are closely related to the known pharmacological effects of the drug. Therefore, many predict. This type of activity is very common and accounts for 70% – 80% of all adverse events.
However, in recent years there has been an increase in strictness and medicine which are used in the treatment of cancer and inflammatory diseases.
This is mainly because new advances in medicine have increased its therapeutic tools.
Currently, treatment is not limited to chemotherapy, but natural drugs are also used.
In this sense, it is very important, if possible, to make a diagnosis that is appropriate and accurate as possible due to these complications.
- “Sometimes it is necessary to move forward, and even when it comes to the disease of drug allergy, it is necessary to do desensitization or to be given the respect of tolerance said medicine to be able to give it again,” explains Dr. Ortega.
